The Technical Vault
Sterile 70% IPA · Routine/Intermediate Disinfection Support · Large-Format Trigger Spray
Texwipe TX3273 Sterile 70% IPA Isopropanol Alcohol Solution (32 oz. Trigger Spray)
Texwipe TX3273 is a sterile, ready-to-use solution of 70% USP-grade isopropanol (IPA) and 30% USP-purified water,
packaged in fully assembled 32 fl oz (946 mL) trigger-spray bottles for controlled-environment wipe-downs, pass-through prep, and routine
cleaning where repeatable wetting, low residue, and lot-level traceability are essential.
At-a-glance (published attributes)
- Composition: 70% by volume USP-grade isopropanol + 30% USP-purified water
- Filtration: 0.2 µm filtered (submicron filtered)
- Sterilization / sterility assurance: Gamma-irradiated; Sterility Assurance Level (SAL) 10−6
- Format: Fully assembled 32 fl oz (946 mL) trigger spray bottle
- Packaging: Double-bagged in solvent-safe packaging (controlled entry support)
- Case pack: 12 poly bottles per case (32 oz trigger spray bottles)
- Sprayer behavior: Adjustable, non-atomizing spray; stream delivery or coarse spray
- Identification: Bottle identification dots (for segregation in multi-chemistry programs)
- Traceability: Lot coded with expiration date; certificates referenced for QA recordkeeping
- Shipping constraint: Ground shipping only (Consumer Commodity / ORM-D handling)
1) Where TX3273 fits in a contamination control program
Sterile 70% IPA is commonly used as a routine or intermediate step in contamination control programs to support consistent wipe-down of
work surfaces, equipment exteriors, carts, and pass-through staging. The 32 oz format is often selected when programs want
fewer bottle change-outs and consistent application across larger areas—while still maintaining controlled-entry packaging and lot traceability.
Important scope note (accuracy-first)
70% IPA is not a sporicide. Many validated programs use IPA for routine/intermediate disinfection and implement a separate
sporicidal agent on a defined schedule as part of a rotation. Follow your site’s contamination control strategy and validation protocol.
2) Standards alignment (USP, ISO, Annex 1) — educational reference
USP <797> and USP <800> expect cleaning/disinfection activities to be controlled through written procedures using appropriate
agents and PPE for the task and risk profile. EU GMP Annex 1 reinforces the need for a robust contamination control strategy,
validated disinfection processes, and disciplined operator behavior in Grade A/B environments. ISO cleanroom operations guidance supports
establishing an operations control program covering personnel practices, cleaning, and material movement.
Key compliance reality: these frameworks do not “approve” a specific brand or sprayer format. Facilities are responsible to
select, validate, document, and train on the exact products and methods used in their rooms.
3) Application technique (what drives repeatable outcomes)
A. Prefer “spray-to-wipe” in critical zones
Where feasible, apply IPA onto a sterile, low-linting wiper and then wipe the surface. This improves saturation control and reduces
overspray and airborne droplets—especially near open components, sensitive assemblies, and airflow paths.
B. Use stream vs. coarse spray intentionally
Stream delivery supports precise wetting (ports, seams, targeted contact areas). Coarse spray supports larger areas, followed by wiping to
distribute evenly and remove loosened residues. Define “how much” and “how far” in your SOP to prevent pooling or drip transfer.
C. Wipe pattern discipline
Use straight-line, overlapping strokes and rotate to a fresh wiper face frequently. Avoid back-and-forth scrubbing with a loaded wipe.
Replace wipes when they become visibly soiled, over-saturated, or dry out below effective use.
4) Donning discipline & PPE interface control
In critical environments, audits frequently identify failures tied to touch events (adjusting eyewear/hoods, contacting non-controlled
objects, or poor glove–sleeve overlap). Ensure personnel are fully gowned before introducing sterile solutions into ISO-classified areas.
Many aseptic programs don sterile gloves last, then sanitize gloved hands with sterile IPA at defined intervals per SOP.
5) System pairings (commonly validated companions)
TX3273 is most effective when paired with cleanroom consumables engineered for controlled wiping and low residue transfer.
Final selection must match your ISO class, surface materials, disinfectant rotation strategy, and SOP validation.
6) Why customers standardize the 32 oz trigger format
- Fewer change-outs: supports longer work periods before bottle replacement in high-usage wipe-down areas.
- Repeatable dosing: adjustable spray supports consistent wetting when distance and pattern are standardized in SOP.
- Clean entry readiness: double-bagged, solvent-safe packaging supports staged de-bagging practices.
- Traceability: lot coding and expiration dating support QA recordkeeping in validated programs.
7) Safety and handling (non-negotiables)
Flammability & SDS
70% IPA is a highly flammable liquid and vapor. Control ignition sources, use appropriate ventilation, and follow your site’s PPE/EHS
program. Always refer to the current SDS for hazard classification, handling, storage, spill response, and disposal guidance.
Disclaimer: This Technical Vault content is provided for educational and reference purposes only. It does not constitute regulatory,
quality, engineering, environmental health & safety, or legal advice. Cleaning agents, contact times, wiping techniques, PPE requirements,
disinfectant rotation, and all related procedures must be defined, validated, and documented by the end user in accordance with internal SOPs,
risk assessments, and applicable standards and regulations. Always follow manufacturer instructions and the current SDS.
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