Texwipe TX3210 SterileWipe HS II (12" × 12") is a dry, sterile cellulose/polyester nonwoven engineered for the situation where the wiping task is inseparable from the sterility framework. Many facilities can clean effectively with a variety of non-sterile wipes; what breaks programs is controlled entry into the suite, repeatable documentation, and performance that stays intact once liquid hits the substrate.

TX3210 is positioned as an economical sterile “workhorse” for spill control and routine wipe-downs in ISO 5 (Class 100) through ISO 8 (Class 100,000) areas, including sterile gowning rooms and production-support cleaning where absorbency and speed matter—but the wipe still must behave like a controlled consumable with traceability.

TX3210 is best used for spill control, general-purpose sterile wipe-downs, and cleaning/polishing of equipment and environmental surfaces during and following production flow—especially when the wipe must be introduced into sterile areas using staged packaging and a documented sterility posture. It is also commonly selected for wipe-downs in sterile gowning rooms where wet strength and predictable behavior reduce rework and “wipe shredding” events.

TX3210 typically earns its place based on controls that directly reduce aseptic and cleaning variability:

• Validated sterility posture: gamma irradiated to 10⁻⁶ SAL (sterility assurance level) with sterility assurance supported by audits and lot-level documentation.
• Documentation that accelerates investigations: lot-specific information, Certificate of Processing (radiation dosage), Certification of Compliance, and expiration dating on package.
• Substrate architecture built for wet work: hydroentangled, binder-free 55% cellulose / 45% polyester blend designed to combine absorbency with wet strength.
• Compatibility with common disinfectant workflows: positioned as chemically resistant for exposure to typical cleanroom cleaning/disinfecting solutions (e.g., bleach, phenols, quats).
• Controlled entry by packaging design: packaging permits alcohol wipe-down of the exterior bag before introducing the inner bag into sterile suites.
• Country-of-origin control: listed as Made in the USA for programs that manage origin as a purchasing/quality attribute (confirm via receiving documentation where required).

“Sterile nonwoven wiper” is still too broad. What matters is how the fabric behaves when it is folded, wetted, and pushed into corners. TX3210 uses a hydroentangled (spunlace) blend rather than a binder-heavy construction. Hydroentanglement mechanically entangles fibers, which reduces one common source of variability—chemical binders—while improving integrity under wet wiping.

The blend ratio is intentional. Cellulose drives rapid wet-out and high sorption for aqueous spills and solution pickup. Polyester contributes tensile strength so the wipe remains intact when saturated and when operators increase wiping force during fast turn events.

Practical control note: no wiper is truly “lint-free” in every process condition. The control target is low-linting performance in your use window—pressure, texture, wetness, and face-rotation discipline are typically the dominant drivers.

For validation-sensitive facilities, treat published values as a qualification starting point rather than a contractual guarantee. The decision logic is still useful: evaluate releasables (particles/fibers), residues (NVR), and ions against your surface sensitivity and acceptance criteria.

• Sorptive capacity: typical 320 mL/m² with a typical <0.3 s sorptive rate (fast wet-out helps reduce “multiple-pass spread” during spill response).
• Particles (LPC): typical 80 × 10⁶ particles/m² (≥0.5 µm).
• Fibers: typical 70,000 fibers/m² (≥100 µm).
• NVR (nonvolatile residue): typical 0.01 g/m² (IPA) and 0.03 g/m² (DI water) extractants.

In aseptic and near-aseptic workflows, wipes fail more often due to handling than substrate choice. TX3210’s packaging is designed to support controlled transfer: the exterior bag can be alcohol-wiped before the inner bag is introduced into the sterile suite. That reduces a common “quiet failure mode”—introducing touch contamination on packaging that becomes part of the suite environment.

Documentation is not an administrative extra; it is a change-control tool. Lot-specific labeling, a Certificate of Processing (radiation dose), Certification of Compliance, and an expiration date reduce ambiguity during investigations and keep sterile consumables aligned with quality expectations.

Typical case configuration is 5 bags of 100 wipes per case; in practice this supports kitting and controlled issue without forcing bulk exposure at the wipe station.

TX3210 performs best when technique treats the wipe as a controlled tool rather than a disposable rag. Use folding discipline to keep clean faces available and to prevent redeposition.

• Quarter-fold for face control: build multiple clean faces and treat each face as single-pass for critical wipe-downs.
• Directional wiping: use straight, overlapping, single-direction strokes; avoid back-and-forth scrubbing unless an SOP explicitly requires it.
• Wetness discipline: aim for damp wiping (or controlled dwell for disinfectants) and change faces before the wipe becomes saturated.
• Aseptic entry workflow: wipe the exterior bag per site practice, stage the inner bag appropriately, and avoid “open bench storage” that collapses packaging intent.
• Discard early: once a face is loaded, it becomes a redistribution tool—especially on stainless and polymer surfaces where films smear.

Sterile wipes become contamination sources in predictable ways: overworking one face, reintroducing packaging contamination into the suite, inconsistent disinfectant dwell, and “wipe shredding” when a substrate loses integrity under wet wiping. TX3210’s hydroentangled blend is designed to balance absorbency with wet strength, while the sterile packaging and documentation posture reduce handling-driven variability.

• Overworking a saturated face: tighten face-life rules and stage more wipes instead of increasing pressure.
• Dragging dissolved soils: avoid re-wetting mid-pass; complete a pass, rotate, then re-wet if the SOP requires.
• Packaging-driven contamination: keep staged introduction disciplined; do not bypass outer-bag wipe-down logic.
• Disinfectant inconsistency: standardize mixing/labeling and contact time; then wipe with fresh faces to remove residues after dwell.

The most defensible comparisons are to other sterile, gamma-irradiated cleanroom nonwoven wipe programs intended for ISO 5–8 cleaning and spill control.

Contec SterileSorb (sterile nonwoven wipe program) is a close comparator when facilities want a sterile, absorbent nonwoven with controlled packaging and documentation intended for aseptic environments.

Berkshire Gamma Wipe 67 (sterile cleanroom wiper family) is an appropriate comparator when programs emphasize gamma-irradiated sterility posture and want a sterile nonwoven positioned for controlled areas.

TX3210 is a strong choice as the sterile, absorbent, general-purpose wipe for ISO 5–8 operations where the facility needs a balance of spill response, wet strength, and documented sterility controls. Use it for sterile gowning-room wipe-downs, production-support cleaning, and routine sterile housekeeping—then keep role clarity in the program: define when TX3210 is the workhorse wipe, when a sealed-edge polyester knit is the finishing control, and when sampling requires method-aligned consumables rather than general-purpose wipes.

• SOSCleanroom product page: “Texwipe TX3210 SterileWipe HSII 12" × 12" Cellulose and Polyester Cleanroom Wiper” (packaging, ISO class listing, features/benefits, applications, country of origin). https://www.soscleanroom.com/product/wipers/texwipe-tx3210-sterilewipe-hsii-12-x-12-cellulose-and-polyester-cleanroom-wiper/
• ITW Texwipe technical datasheet: “SterileWipe HS II TX3210” (substrate composition and construction; sterility posture; typical performance metrics including sorption, LPC/fibers, NVR; documentation and packaging framework). https://www.soscleanroom.com/content/texwipe_pdf/3210.pdf
• Comparator reference: Contec “SterileSorb” sterile wipe program (category positioning and sterile wipe framework). https://contecinc.com/products/sterilesorb/
• Comparator reference: Berkshire “Gamma Wipe 67” sterile cleanroom wiper family (category positioning and gamma-irradiated sterile wipe framework). https://berkshire.com/products/gamma-wipe-67/