The Technical Vault
By SOSCleanroom
TX3252 Sterile AlphaSat with AlphaSorb HC: Two-Ply Polyester, 70% IPA Pre-Wetted Wiper for High-Sorption Sterile Wipe-Down Control (ISO 4–8)
Last reviewed: Jan. 4, 2026 | Audience: contamination control, cleanroom operations, EHS, quality
TX3252 is a sterile, pre-wetted cleanroom wiper built for the realities of pharmaceutical and life-science wipe-downs: frequent alcohol use, repeatable solvent delivery, and high fluid demand without improvising with squirt bottles and ad-hoc saturation. It uses a two-ply, cleanroom-laundered 100% polyester construction and arrives saturated with a 70% isopropyl alcohol (IPA) / 30% water solution intended to standardize wetting at the point of use.
Operationally, TX3252’s value is control. A consistent pre-wet load helps reduce operator variability, supports more predictable residue removal and surface wetting behavior, and improves audit readiness when your program expects sterile packaging, lot traceability, and documentation discipline in the same workflow that needs “grab-and-go” efficiency.
What it’s for
Routine sterile wipe-downs and alcohol cleaning tasks in controlled environments, including transfer disinfection, equipment and cart wipe-downs, and removal of light films and handling residues where a validated sterile, pre-wetted delivery format is preferred. TX3252 is commonly selected when teams want a high-sorption polyester platform for solution application and pickup on benches, process-support equipment, pass-through items, and environmental surfaces.
Decision drivers
TX3252 is usually the right call when the process need is “high sorption + sterile pre-wet control,” and the quality system wants repeatable, documented wiping—not operator-dependent wetting.
- Pre-wetted 70% IPA format: Delivers a defined wetting profile per wipe, reducing variability vs. manual wetting and helping control solvent handling at the bench.
- Two-ply 100% polyester: A high-absorbency platform engineered for spill control, cleaning, and solution application with strong chemical resistance across common cleanroom solvents.
- Edge strategy (cut edge): A cut-edge two-ply knit designed for durability on more abrasive surfaces; qualification should consider whether the step is a “bulk wipe-down” vs. a defect-sensitive final pass.
- Sterility framework: Gamma irradiated with sterility assurance positioning (SAL 10−6) and case-level documentation expectations that support sterile workflows.
- ISO program placement: Commonly positioned for ISO Class 4–8 programs, including EU Grade A–D in aligned workflows where the wiping method is validated and controlled.
- Packaging discipline: Flatpack configuration supports orderly dispensing and minimizes “open time” risk when paired with a point-of-use handling rule.
Materials and construction
TX3252 is built on a two-ply 100% polyester wiper platform (AlphaSorb HC) that is cleanroom laundered to target low residues and ionic contamination typicals. Two plies increase bulk and fluid handling capacity—useful when the job is equal parts “apply solution” and “pick up what the solution mobilizes.” Polyester’s chemical resistance is a practical advantage when your wipe-down set includes IPA, ethanol, acetone, and degreasers under validated controls.
The cut-edge construction is a deliberate tradeoff: it supports a robust wipe on more abrasive surfaces, but it also means the edge zone should be treated as a controlled variable (pressure, stroke pattern, fold method). Programs that require the tightest edge control in the highest-risk final passes often qualify a sealed-edge platform for those steps and keep TX3252 for controlled alcohol wipe-downs and solution handling.
Specifications in context
SKU: TX3252
Type: Pre-wet wiper (sterile)
Wiper size: 12" x 12" nominal (31 cm x 31 cm)
Material/structure: 100% two-ply polyester (cleanroom laundered)
Edge: Cut edge
Pre-wet solution: 70% IPA / 30% water (manufacturer literature specifies DI water; product literature also references high-purity solution filtration)
Cleanroom environment: ISO Class 4–8 (Class 10–100,000), aligned to EU Grade A–D program placement when validated
Packaging (case): 5 flatpacks of 25 wipers per case (125 wipers/case)
Shelf life (sterile, pre-wetted): 3 years from date of manufacture (confirm on lot documentation)
Cleanliness and performance metrics
For cleanroom wiping, the metrics that move outcomes are particle/fiber release, nonvolatile residue (NVR), and ions. Manufacturer values are typically reported as “typicals” tied to published test methods (commonly IEST-RP-CC004.3 and ASTM E2090) and should be used as a qualification starting point—not a substitute for site validation on your surfaces and chemistries.
Performance (AlphaSorb HC / TX3252 family typicals):
Absorbency (sorptive capacity): 680 mL/m2
Absorbency (sorptive rate): < 1 second
Basis weight: 214 g/m2
Contamination (AlphaSorb HC / TX3252 family typicals):
LPC (≥0.5 µm): 8.2 x 106 particles/m2
Fibers (>100 µm): 500 fibers/m2
NVR (IPA extractant): 0.02 g/m2
NVR (DIW extractant): 0.01 g/m2
Ions (ppm): sodium 0.05; potassium 0.07; chloride 0.02
Product-specific TX3252 typicals (legacy datasheet example):
Sorptive capacity: 300 mL/m2 | Sorptive rate: 5.1 seconds | Basis weight: 131 g/m2
Particles 0.5–5.0 µm: 5 x 106 particles/m2 | 5.0–100 µm: 220,000 particles/m2 | Fibers (>100 µm): 120 fibers/m2
NVR: IPA 0.06 g/m2 | DIW 0.02 g/m2
Ions (ppm): sodium 0.25 | potassium 0.08 | chloride 0.05
Practical interpretation: use the most current manufacturer TDS for baseline expectations, then qualify with your sampling plan and acceptance criteria. If your program trends particles or residues, treat a TDS revision as a change-control input.
Pre-wetted IPA control, contact-time discipline, and handling
Pre-wetted wipes reduce one major source of variability (operator wetting), but they introduce a different control point: evaporation and “open time.” A flatpack only protects the wetting profile while it stays properly closed and while operators avoid staging wipes on benches or carts. In sterile programs, handling and presentation are often as important as the substrate—define how the pack is opened, how wipes are dispensed, and when a wipe is discarded so the method stays consistent across shifts.
Rule of thumb: Open the flatpack only at point-of-use, remove one wipe without “digging,” reseal immediately, and keep the surface wet for your site’s validated contact time (do not assume “a quick wipe” meets your program’s requirement).
Best-practice use
The wiper is only half the control. Standardize fold geometry, stroke pattern, and discard triggers so the wiping method is repeatable and defensible in investigations and audits.
- Fold into a controlled pad: Use a consistent fold (multiple clean faces) and a defined leading edge; avoid bunching that concentrates pressure and increases streaking risk.
- One-direction, overlapping strokes: Use linear passes to move contamination off the surface. Avoid circular scrubbing that redistributes residues.
- Face-rotation rule: Rotate to a fresh face early. A loaded wipe can redeposit residues and smear softened films—especially as IPA flashes off.
- Bulk first, detail second: Remove gross residues with a defined first pass, then re-wipe with a fresh face for the “finish” pass if the step is defect-sensitive.
- Control the edge zone: For corners and hardware, reduce pressure and shorten strokes; keep the wipe folded so the working edge is supported by multiple layers.
- Dispose by control trigger: Define a discard trigger (area, time, or stroke count). Do not extend use because “it still feels wet.”
Common failure modes
Flatpack left open (evaporation drift): Wipes become inconsistently wetted and can shift from “wet wipe” to “smear pass.” Fix with a reseal rule and a maximum open-time expectation at the point of use.
Overusing one wipe: High sorption can become cross-contamination when the wipe is loaded. Fix with a face-rotation rule and a discard trigger.
Assuming IPA is a universal disinfectant: IPA is widely used for wipe-downs, but your microbial control strategy and validated contact-time requirements govern whether it is appropriate for the step. Fix with program clarity (what the step is achieving) and method validation.
Using a cut-edge wiper for the tightest final pass: Many programs use cut-edge platforms successfully, but the most defect-sensitive final-pass steps may require a sealed-edge strategy. Fix by separating “general wipe-down” from “final-pass” wiping in your program design.
Shipping/handling surprises: Alcohol pre-wets often ship under hazmat constraints. Fix by planning reorder points and shipment lanes so you do not force a last-minute substitution.
Closest competitors
Contec PROSAT® Sterile Sigma™ wipes (cellulose/polyester hydroentangled, presaturated 70% IPA/30% DI water): Mechanism is a hydroentangled nonwoven blend optimized for economical transfer disinfection and general cleaning. Compared with a two-ply polyester platform, qualification often comes down to linting/fiber behavior on your surfaces, pickup of specific residues, and whether the substrate chemistry (cellulose content) fits your process risk.
Berkshire Sterile SatPax® 670 (55% cellulose/45% polyester hydroentangled, presaturated 70% IPA/30% DI water): Mechanism is a high-saturation presaturated nonwoven designed for regulated wipe-downs. Programs commonly compare “wet delivery consistency,” particle/fiber behavior, and how the wipe handles abrasive wiping and repeated passes relative to a two-ply polyester approach.
Where it fits in a cleanroom wiping program
TX3252 fits as a “controlled alcohol wipe-down” tier in ISO 4–8 programs—particularly where teams want to reduce operator-dependent wetting variability and keep sterile packaging and documentation aligned with daily wipe-down reality. Many facilities succeed by defining TX3252 for routine wipe-downs, transfer disinfection, and solution handling, while separately qualifying a sealed-edge platform for the most defect-sensitive final-pass steps or the highest friction edge-contact wiping.
Terminology note: Engineered for low-linting performance; no wiper is truly “lint-free” in every process condition.
Source basis
- SOSCleanroom product page (TX3252): https://www.soscleanroom.com/product/wipers/texwipe-tx3252-sterile-alphasat-with-alphasorb-12-x-12-polyester-wiper-pre-wetted-70-ipa/
- SOS-hosted Texwipe datasheet copy (TX3252; Effective Aug. 2012): https://www.soscleanroom.com/content/texwipe_pdf/3252.pdf
- Texwipe product page (TX3252): https://www.texwipe.com/sterile-alphasat-with-alphasorb-hc-tx3252
- Texwipe Technical Data Sheet (AlphaSorb HC; TEX-LIT-TDS-007 Rev.00-02/17): https://www.texwipe.com/images/uploaded/documents/Wipers/Texwipe-AlphaSorbHC-TDS-ENG.pdf
- IEST recommended practice referenced by manufacturer test methods (IEST-RP-CC004.3): https://www.iest.org/
- ASTM standard referenced for particle/fiber release counting (ASTM E2090): https://www.astm.org/
- Contec PROSAT Sterile Sigma wipes product page: https://cleanroom.contecinc.com/product/1779525026
- Berkshire Sterile SatPax 670 product PDF: https://berkshire.com/wp-content/uploads/2024/01/Sterile-SatPax-670.pdf
Source: SOSCleanroom Technical Vault | Last reviewed: Jan. 4, 2026
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