DWK 218505453 DURAN GL 45 Hydra HPLC Purging Bottle, square, clear, with 4 GL 45 side necks, 1000 mL

DURAN® 218505453 HYDRA is a 1,000 mL square clear borosilicate glass 3.3 HPLC purging bottle. It provides five GL 45 access points - a central neck and four side necks - on one common liquid chamber. The design supports HPLC mobile-phase storage and delivery, mobile-phase replenishment, and instrument-line purging arrangements.

DWK positions its multi-neck bottle as a more convenient way to use GL 45 HPLC connection caps while reducing the need to disturb an existing solvent-delivery line. With appropriate caps and connections, restricting open ports may help manage air intake, contamination, VOC escape, and spillage.

The four side necks and the central neck connect to the same 1,000 mL reservoir. This allows additional GL 45 connection options, not separation into five different liquids. A laboratory might dedicate one fitted cap to mobile-phase delivery and another to an approved addition or purge-related operation, depending on its validated setup.

In HPLC setup, purging commonly means flushing existing liquid out of the solvent-delivery lines and replacing it with the new mobile phase. The DWK technical flyer explains this as a line-flushing step performed as part of setting up the HPLC system.

• Reservoir role: Hold compatible mobile phase and provide GL 45 access points.
• Delivery role: Suitable connection caps and tubing interface with the HPLC system.
• Purging role: The HPLC instrument or validated apparatus moves the solvent through its lines.
• Connection role: Additional necks allow flexible lines or access without automatically exposing every opening.
• Safety role: Keep unused ports closed and use compatible seals and ventilation.
• Not included by implication: Pump, degasser, gas sparger, PTFE tubing, solvent filter, three-port delivery caps, or fittings.

Confirm the line-purging sequence and any requirement for inert gas, degassing, solvent filtration, and pressure equalization in the specific instrument’s operating procedure.

DWK’s exact-SKU data lists PP (polypropylene) as the cap and closure material, and its literature shows capped examples of the multi-neck HYDRA. However, neither the current product page nor the reviewed flyer specifies how many basic caps are physically included in a case of one. A photograph does not independently establish the supplied cap count.

The manufacturer describes the ability to accept up to five standard GL 45 HPLC connection caps, which means the ports have that thread compatibility. It does not establish that those specialized caps are furnished. DWK separately identifies a three-port GL 45 HPLC delivery cap 292312801 as a recommended accessory.

The bottle body is clear DURAN borosilicate glass 3.3. DWK identifies this material as a low-inorganic-ion-extractables glass suitable for many chromatography solvent reservoirs. Its multi-neck literature links the glass classification to ISO 3585 and ASTM E438 Type I, Class A low-expansion borosilicate glass.

Glass is broadly resistant to many water-based and organic reagents but is not universally inert. Hydrofluoric acid and some strong heated alkaline conditions can attack borosilicate glass. Avoid converting the general glass standard into an assertion that every HPLC solvent mixture is compatible.

DWK specifies a 94 x 94 mm square footprint, 217.5 mm height h, 222.5 mm overall height, 183 mm h1 drawing dimension, and 30 mm mouth inside diameter. Its multi-neck flyer uses 222.5 mm as the overall bottle height reference. Allow additional space for the chosen connection caps, solvent tubing, or gas/vent connections.

The white enamel graduated scale runs from 100 to 800 mL in 100 mL increments. The nominal bottle capacity is 1,000 mL, which is not the same as the highest marked graduation. Graduations are intended for convenient content estimation rather than class-A volumetric accuracy.

DWK states that the HYDRA bottle features a Retrace Code supporting manufacturing-lot traceability and a corresponding certificate. The general DWK certification page explains how printed bottle codes can be used for manufacturing-lot reference and document retrieval.

• Find and record the printed Retrace Code from the delivered bottle or packaging.
• Use DWK’s certificate process with the article number and required lot identifier.
• Retain the retrieved manufacturing-lot documentation according to the quality system.
• Distinguish manufacturing-lot traceability from solvent purity testing or HPLC method suitability.
• Do not assume the bottle arrives with a separate printed Certificate of Analysis unless confirmed.

The Retrace Code is a production traceability feature. It does not certify the assembled system as sterile, pressure-rated, VOC-tight, or validated for a particular chromatographic solvent.

A complete HPLC solvent supply system may contain DURAN glass, polypropylene or other cap resins, fluoropolymers, elastomeric seals, tubing, and solvent filters. The exact configuration governs compatibility; the base glass material cannot qualify every component.

The current 218505453 manufacturer page does not publish a specific autoclavability or sterile-status field. Although DURAN borosilicate 3.3 is used widely in heat-tolerant laboratory glassware, this does not automatically establish an approved autoclave procedure for the five-neck bottle with selected caps and tubing.

• Exact sterilization cycle: Not established for the as-delivered HYDRA assembly.
• Sterile packaging: No exact-SKU sterile supply claim verified.
• Pressure/vacuum rating: Not established; do not operate as a pressurized reaction vessel.
• Sealed heating: Avoid pressure buildup; use manufacturer-approved venting and process controls.
• Thermal shock: Handle temperature changes and different cap materials cautiously.
• Glass inspection: Check the base and all side-neck junctions for chips or cracks.
• Protect personnel: Follow appropriate PPE and solvent spill response protocols.

The 2 L side-neck bottle and the three-port HPLC cap are distinct products; no separate reservoir or accessory is part of the verified one-bottle 218505453 purchase unit. The caps used for actual HPLC operation should be selected and priced intentionally.

1. Receiving: Confirm DURAN 218505453 and one square 1 L bottle.
2. Inspect glass: Check all five necks, joints, base, rim, and threads for chips or fractures.
3. Verify package contents: Count delivered caps and compare with the supplier’s order confirmation.
4. Document the lot: Record the Retrace Code and retrieve applicable manufacturer certificate.
5. Confirm fit: Check the 94 x 94 mm base and 222.5 mm overall height plus fittings and tubes.
6. Define port use: Assign the connection and closure type for each of five GL 45 openings.
7. Review solvent compatibility: Check glass, cap, seal, tube, and fitting materials.
8. Prepare mobile phase: Follow the method’s filtration, degassing, and solvent purity requirements.
9. Cap unused ports: Reduce contamination and vapor exposure, consistent with method and safety procedures.
10. Purge the HPLC lines: Use instrument instructions and verify correct fluid delivery.
11. Check graduations: Treat 100-800 mL scale as approximate, not calibrated dispense volume.
12. Follow safety controls: Use appropriate containment, flammable-solvent storage, and waste procedures.

Inspect and clean the bottle according to an approved laboratory process. Prior mobile phases may affect new samples through residue, carryover, extractables, or contaminated connection fittings. Cleaning of the glass body does not itself demonstrate cleanliness of caps, tubing, or filters.

• Remove and handle connection components according to their manufacturer instructions.
• Check all necks, especially side-neck junctions, for damage and retained contamination.
• Use cleaning agents and rinse procedures compatible with borosilicate glass and each separate component.
• Prevent residues from dried salts or buffers at rim and threaded surfaces.
• Use method-qualified water or solvent rinses and system blanks where required.
• Retain manufacturing-lot and cleaning records under the laboratory SOP.
• Do not apply unverified pressurized cleaning or a fully capped steam-sterilization process.

The manufacturer’s care-and-maintenance reference provides general handling guidance; the laboratory must validate any reuse cycle relevant to its solvents and analytical performance.

• Not five independent reservoirs: Five necks access one liquid chamber.
• Not an active HPLC purging device: No pump, degasser, or programmed purge function is established.
• Not guaranteed with five caps: Exact supplied cap count is unconfirmed.
• Not an included three-port delivery cap: DWK lists 292312801 as a recommended accessory.
• Not certified airtight: No complete-system VOC leakage or vapor-tight result established.
• Not a pressure/vacuum vessel: No exact rating established.
• Not a calibrated volumetric flask: 100-800 mL graduations are for estimating volume.
• Not a sterile product claim: Sterility is not specified.
• No verified autoclave cycle: Exact-SKU finished-system process not specified.
• No universal solvent compatibility: Consider caps, liners, seals, and tubing.
• No certified ion-extractables figure: Low-extractables statement is qualitative.
• No cap-and-tubing clearance guarantee: Depends on assembled configuration.
• No verified carton size or gross weight: Request current logistics information.
• No claim of 1,000 mL marked range: Graduations stop at 800 mL.

What is DURAN 218505453?

A 1 L clear borosilicate glass 3.3 square HYDRA HPLC purging bottle with five GL 45 necks and a case quantity of one.

How many GL 45 necks are there?

Five: one main central opening and four side necks.

Are there five separate chambers?

No. All five necks communicate with the same 1 L reservoir.

What does HPLC purging mean?

Flushing the system’s lines so previous solvent is replaced by the new mobile phase; the HPLC system performs the flushing.

Does the bottle perform purging by itself?

No pump, automatic purge mechanism, or degasser is established as included.

Are five caps included?

DWK lists PP closure material but does not clearly specify how many caps come with the exact 218505453 order unit. Confirm before ordering.

Does it include HPLC tubing or connection caps?

No inclusion has been established for tubing, fittings, or the specialized three-port HPLC delivery cap.

What glass is used?

Clear DURAN borosilicate glass 3.3, identified by DWK with ISO 3585 and ASTM E438 Type I, Class A.

What is the square footprint?

94 x 94 mm.

How tall is the bottle?

DWK lists 217.5 mm catalog height and 222.5 mm overall height. Allow more clearance for installed caps and tubing.

What is the mouth inside diameter?

The manufacturer lists 30 mm.

What are the graduation marks?

White enamel, 100–800 mL in 100 mL steps.

Is the 1,000 mL bottle a calibrated volumetric vessel?

No calibrated volume tolerance is supplied. Nominal 1 L capacity is distinct from the highest 800 mL graduation.

What is the Retrace Code?

A code for manufacturing-lot traceability and corresponding manufacturer certificate lookup.

What is the three-port accessory part number?

DWK lists DURAN 292312801, a separate GL 45 HPLC cap for 3.2 mm outside-diameter tubing.

Does the bottle have low ion extractables?

DWK describes the borosilicate 3.3 glass as having a very low inorganic ion extractables profile; no exact numerical limit is established here.

Does it reduce solvent vapor exposure?

DWK states that a capped configuration reduces the risk of VOC escape and spills; no exact-system quantitative emission guarantee is established.

Can 218505453 be autoclaved?

The exact product listing does not specify an autoclave cycle or full-assembly rating. Confirm bottle, caps, and tubing suitability before any processing.

Is this supplied sterile?

No manufacturer sterile claim was confirmed in the reviewed exact-SKU data.

Can this be pressurized or placed under vacuum?

No pressure or vacuum rating is established for the exact five-neck assembly.

What is the purchase quantity?

One bottle per case.

How is this different from the 2 L side-neck model?

The DURAN 219900701 is a 2 L GL 45 bottle with one additional side neck, rather than this 1 L square five-neck HYDRA.

• DWK DURAN Multi-Neck HPLC Bottles technical flyer (PDF): View HYDRA bottle design, five GL 45 necks, HPLC purging, and the recommended three-port cap. Product-specific manufacturer technical literature; the delivery cap is listed as a recommended accessory, not a confirmed included item.
• DWK Glass Types & Properties: Review borosilicate 3.3 characteristics and material guidance. Generic glass reference; does not establish a finished five-neck assembly temperature or pressure rating.
• DWK Certification: Learn about DURAN Retrace Code and manufacturing-lot certificate lookup. A traceability reference, not a claim that a separate CoA ships in every case.
• DWK Care & Maintenance: Review laboratory glassware inspection and handling guidance. General advice; the precise cap assembly and cleaning process must be qualified.

Documentation scope: The PDF is a DWK manufacturer technical flyer, not a shopping or checkout page. The other links are manufacturer technical guidance. Manufacturer product-detail and purchasing pages are deliberately excluded.

For pricing, availability, GL 45 caps, or technical documentation: Email Sales@SOSsupply.com or call (214) 340-8574.

Last updated: October 28, 2026

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