DWK WHEATON Serum Bottle

These WHEATON® serum bottles are molded borosilicate glass containers identified by DWK for sample storage, lyophilization, and pharmaceutical-container applications. The eight variants share a 20 mm crimp finish but differ in capacity, body dimensions, color, and case quantity.

A complete container system includes more than the bottle. Select the stopper, aluminum seal, preparation method, filling conditions, and storage requirements around the intended contents and application.

DWK's current product pages identify the bottles as molded borosilicate glass conforming to USP Type I requirements. The manufacturer-supplied PIM additionally identifies WHEATON® 400 glass for clear bottles and WHEATON® 500 glass for amber bottles.

The PIM material fields use Type 1B terminology, while the current product pages use Type 1 borosilicate wording. DWK's glass guide distinguishes ASTM glass classifications from USP classifications. Do not treat those labels as interchangeable descriptions of every glass property.

Review DWK's Glass Types and Properties guide

Confirm the stopper geometry, elastomer, seal style, and crimping tool as a matched system. A shared nominal 20 mm size is not enough to establish compatibility with every stopper construction. Some specialized stopper designs have additional neck-geometry requirements.

The bottle records do not identify an included stopper-and-seal kit. Arrange the closure components required by the approved process rather than treating the bottle case as a complete sealed-container system.

DWK offers different aluminum seal styles. Open-top seals expose the stopper for syringe access; tear-off styles permit removal of the seal; flip-cap styles provide a different access and tamper-evidence arrangement.

Choose the access method together with the stopper and intended use. The sealing result depends on the complete assembly and its qualified application, not the aluminum seal alone.

Review WHEATON aluminum seal styles

Use the color required by the method or storage specification. Where light protection is critical, obtain the applicable transmission data and qualify the actual contents and exposure conditions. No wavelength cutoff, percentage of UV blocking, or sample-stability period is established here.

Amber in this listing refers to the 100 mL bottle only. Do not assume that every clear capacity has a corresponding amber option on this product page.

DWK identifies this serum-bottle family as suitable for many lyophilization applications. That product positioning does not specify a universal freeze-drying cycle or establish that every stopper is suitable for partially stoppered processing.

• Confirm equipment fit: Check the actual bottle diameter, height, tray arrangement, and stoppering clearance.
• Define the fill: Establish the process working volume and required headspace rather than using nominal capacity as the fill instruction.
• Choose the closure: Verify stopper design and compatibility with the bottle neck and processing sequence.
• Qualify the cycle: Validate the formulation, freezing, drying, and final closure process for the selected container.

These checkpoints are facility-selection guidance, not a manufacturer-prescribed cycle or a guarantee that all eight sizes behave identically in the same process.

The manufacturer lists Autoclavable: Yes for all eight bottle variants. This establishes the stated capability of the glass bottles, not the suitability of every selected stopper, seal, filled formulation, or assembled load.

No supplied-sterile designation, sterility assurance level, endotoxin limit, or validated depyrogenation cycle is identified in the reviewed SKU records. Shrink-wrapped partitioned packaging is not identified as a sterile barrier.

The stated 5–125 mL values are manufacturer container capacities. The reviewed records do not establish calibrated volume tolerances, recommended working fills, or brimful capacities.

Bottle dimensions change with capacity even though the crimp finish remains 20 mm. Recheck racks, trays, labels, sample-handling equipment, and stoppering arrangements when changing size.

Evaluate compatibility with both the glass and the selected elastomeric closure. Where relevant, establish the required extractables, leachables, adsorption, particulate, and sample-stability data for the actual formulation and storage period. USP Type I glass alone does not answer every container-compatibility question.

DWK describes shrink-wrapped partitioned modules designed to reduce breakage. Case quantities are 288 for the listed clear 5, 10, 20, 30, and 50 mL variants, and 144 for the listed clear 100 mL, clear 125 mL, and amber 100 mL variants.

• Verify identity: Match the received catalog number, color, capacity, and quantity to the order.
• Inspect the package: Investigate damaged cartons, disturbed wrapping, and evidence of broken glass before releasing the material.
• Inspect the bottle: Check the neck and sealing land as well as the body and base.
• Control accessories: Maintain the approved stopper, seal, and crimp-tool configuration.
• Maintain records: Capture received identification, preparation status, and any required manufacturer documentation under the facility's quality system.

The manufacturer's item setup records list room-temperature shipping and storage for the supplied empty bottles. This does not establish the stability period or storage temperature of a filled sample.

These bottle records do not establish a working-pressure rating, centrifuge rating, universal cryogenic-use qualification, or complete transport-packaging approval. Do not transfer leak-test or temperature claims from another WHEATON bottle family.

For sterile manufacturing or injectable-product use, qualify the container, closure system, preparation, filling process, and required documentation. The manufacturer's application description is not a substitute for that qualification.

Individual manufacturer product pages are linked through the SKU numbers in the Product Description table. Specifications were cross-checked against manufacturer-supplied product-information and item-setup records. Qualification checkpoints are application guidance, not additional product certifications.