DWK 225180 WHEATON 12 x 32mm Polypropylene Vial With Insert, Snap/Crimp Finish, 11mm, 300µL

The WHEATON® 225180 is a natural polypropylene chromatography vial with an integrated conical limited-volume well. Its published dimensions are 12 mm diameter × 32 mm height, with a 300 µL insert-size designation and an 11 mm snap/crimp finish.

Rather than requiring a separately installed insert, the vial is manufactured with the conical interior as part of its construction. This design supports collection of smaller samples near the bottom of the vial for suitable chromatography workflows.

In a conventional vial-and-insert assembly, a separate insert is placed inside the sample vial. WHEATON 225180 instead incorporates the conical limited-volume well into the polypropylene vial.

Eliminating the separate insert may simplify sample preparation, but it does not establish a quantified reduction in contamination, analytical carryover, or sample loss. Such improvements must be demonstrated for the laboratory's process.

The manufacturer's 300 µL value is identified as the insert size. It describes the limited-volume interior configuration rather than a documented total capacity for the entire outer vial.

A suitable working volume depends on needle penetration depth, sample geometry, solvent wetting characteristics, required injection volume, and the analytical method.

WHEATON identifies the 225180 with an 11 mm snap/crimp finish. The laboratory must select an appropriate cap and septum assembly for the intended handling or autosampling process.

Snap and crimp closures use different application mechanisms. A closure's nominal 11 mm designation alone does not guarantee a suitable seal, compatibility with the vial geometry, or correct needle access.

• Cap selection: Confirm the closure style and size.
• Septum material: Evaluate sample and solvent compatibility.
• Instrument access: Confirm needle clearance and septum penetration requirements.
• Seal quality: Qualify the assembled vial for the intended storage and injection conditions.
• Processing: Verify the temperature limits of the closure independently from the vial.

DWK identifies polypropylene as a chemically resistant laboratory polymer and lists general PP temperature and autoclavability characteristics in its plastic-resin reference information.

Polypropylene may be appropriate for sample chemistries that do not require a glass container. However, resistance varies with chemical identity, concentration, temperature, and exposure duration.

Where sensitive analytical methods are involved, additional evaluation may be necessary for adsorption, extractables and leachables, sample recovery, and chemical stability.

The 12 × 32 mm form factor is common in chromatography workflows. However, a matching outside diameter and height do not by themselves establish compatibility with every instrument tray, injector, or autosampler needle.

• Tray and holder fit: Verify the actual dimensions against the instrument's accepted vial specifications.
• Needle depth: Confirm suitable access to the integrated conical well without contacting the interior.
• Needle alignment: Evaluate positioning and tolerances through the full injection sequence.
• Injection volume: Establish a suitable working sample volume for the method.
• Closure compatibility: Validate the selected 11 mm cap and septum.
• Analytical performance: Evaluate recovery, contamination, carryover, and stability where relevant.
• Method changes: Requalify when replacing a glass vial or another limited-volume insert system.

The reviewed product documentation does not identify a universal list of approved autosampler models or instrument-specific operating settings.

The manufacturer-supplied 2026 item setup record marks WHEATON 225180 as autoclavable. General DWK polypropylene guidance identifies the material as suitable for steam autoclaving at 121°C.

This general material guidance is not a validated processing protocol for every filled vial, closure, septum, or complete autosampler assembly.

Any cleaning or autoclaving procedure should be qualified for the vial's geometry, the intended contents, and the components exposed to the processing conditions.

The manufacturer's 100-count shelf-pack arrangement is part of the documented 1,000-count case configuration. It does not by itself establish that individual shelf packs are offered as separate purchasing units.

No special sterile-barrier packaging, ISO cleanroom classification, or quantified particulate specification is established by these packaging data.

These products have different integrated limited-volume configurations. Changing insert size may alter the working sample geometry and required autosampler settings.

Contact SOSCleanroom to confirm availability and select the configuration best suited to the laboratory's sample volume.

• Verify identity: Confirm WHEATON 225180, natural PP material, 300 µL insert size, and 1,000-count case.
• Check geometry: Confirm the vial dimensions and 11 mm snap/crimp finish.
• Inspect the vial: Look for deformation, cracking, damage, or contamination.
• Inspect the integrated well: Confirm the conical interior is free from visible damage or obstructions.
• Review closures: Verify separately purchased caps and septa before use.
• Verify sample chemistry: Review PP and closure-material compatibility.
• Maintain records: Follow laboratory acceptance, labeling, and traceability procedures.

The following technical references provide general guidance on polypropylene material properties, cleaning, autoclaving, and chemical compatibility. They are not product purchasing pages.

Documentation boundary: General material guidance does not constitute product-specific certification of analytical recovery, instrument fit, sample stability, or complete-assembly processing performance.

SOSCleanroom can help customers select the appropriate WHEATON limited-volume chromatography vial, compare integrated insert sizes, and identify compatible 11 mm closure systems.