The Technical Vault
By SOSCleanroom
WHEATON 851358
10 mL Capacity
150 mm Length
Virgin PP
Natural Color
Non-Filtered
Bulk Pack
100/Case
WHEATON 851358: selecting the correct 10 mL macrotip for reliable laboratory pipetting
WHEATON® 851358 is a 10 mL disposable polypropylene macro pipette tip supplied by DWK Life Sciences. It is manufactured in a natural-color configuration with a 150 mm nominal length and supplied in bulk packaging containing 100 tips per case.
The tip is intended for appropriately configured macro pipetting instruments. WHEATON's historical pipette-tip selection chart associates this 10 mL tip with selected SOCOREX ACURA manual and electro models and CALIBRA digital macropipettes.
Although tip selection may appear straightforward, the fit between the pipette nozzle and disposable tip can affect aspiration, dispensing, liquid retention, and repeatability. The specified tip capacity must also be distinguished from the pipette's adjustable volume range and calibrated performance.
A separate consideration is the tip's contamination-control configuration. WHEATON's SKU-level selection documentation identifies 851358 as a regular, unfiltered macro tip and does not designate it as sterile, DNase/RNase-free, or pyrogen-free.
Operations takeaway: Confirm three requirements before standardizing WHEATON 851358: 10 mL tip capacity, actual pipette-nozzle compatibility, and the required contamination-control grade. A tip that physically attaches to a pipette is not automatically qualified for its volumetric method or sterile workflow.
Specifications (SKU controls for RFQs, SOPs, and receiving)
- Manufacturer: DWK Life Sciences
- Brand: WHEATON®
- Catalog number: 851358
- Product family: WHEATON Pipette Tips
- Product category: Laboratory liquid-handling consumables
- Tip classification: Macro pipette tip
- Nominal maximum volume: 10 mL / 10,000 µL
- Overall length: 150 mm
- Material: High-grade virgin polypropylene, per manufacturer family description
- Color: Natural
- Construction: Precision injection-molded
- Tip style: Regular macrotip
- Graduations: Not designated as graduated in the manufacturer selection chart
- Filter: No; unfiltered
- Supplied sterile: No sterile designation for 851358 in the manufacturer selection chart
- DNase/RNase-free designation: Not indicated for this SKU
- Pyrogen-free designation: Not indicated for this SKU
- Packaging: Bulk pack of 100 tips
- Quantity per case: 100
- Current SKU-page autoclavability: No product-specific cycle or designation confirmed
- Validated universal pipette compatibility: Not established
- Tip dimensional tolerances: Not provided in reviewed SKU specifications
- Product-specific extractables, endotoxin, or particle limits: Not established in reviewed specifications
Specification-control note: DWK's current online listing provides the 150 mm length, 10 mL volume, natural color, and bulk quantity. Additional information about filtration and sterility comes from WHEATON's detailed tip-selection chart. The current product-family marketing bullets describe features available across different tip products and should not all be applied to 851358.
Polypropylene construction: understanding the material and manufacturing method
WHEATON identifies its pipette-tip family as manufactured from high-grade, virgin, metal-free polypropylene. Polypropylene, commonly abbreviated PP, is a thermoplastic polymer used extensively in laboratory consumables.
The term "virgin" describes material not sourced from previously processed recycled plastic. The manufacturer's "metal-free" description identifies its material-selection approach; it should not be interpreted as a certified zero-metal extractables specification unless a product-specific test report is available.
Precision injection molding allows the manufacturer to control tip shape, nozzle engagement geometry, and the internal fluid passage. Consistent geometry helps support repeatable attachment to an appropriately matched pipette nozzle.
- Base polymer: Polypropylene (PP).
- Material description: High-grade, virgin polypropylene.
- Manufacturing method: Precision injection molding.
- Color: Natural, without a specified colored-tip identification system.
- Mechanical purpose: Form a consistent, disposable fluid-contact tip for a matching pipette nozzle.
- Qualification requirement: Obtain product-specific documentation where extractables, leachables, trace-metal levels, or material formulation requirements govern the application.
Material boundary: The properties of generic polypropylene do not establish a specific chemical resistance rating, biological purity level, sterilization process, or validated extractables limit for every finished polypropylene pipette tip.
Tip geometry: what the 10 mL capacity and 150 mm length mean
The 10 mL designation identifies the tip's nominal maximum liquid capacity. The 150 mm length is the manufacturer's published tip-length dimension.
These measurements do not describe the entire tip geometry. For example, nozzle-engagement diameter, taper, wall thickness, and outlet opening are additional dimensions that can affect fit and liquid-transfer characteristics.
| Attribute |
Published value |
Selection significance |
| Nominal capacity |
10 mL |
Maximum tip-volume classification |
| Overall length |
150 mm |
Tip identification and equipment clearance |
| Color |
Natural |
Visual identification of the specified configuration |
| Nozzle engagement dimensions |
Not published |
Must be established by compatibility guidance |
| Outlet opening diameter |
Not published |
Do not assume a universal flow or droplet characteristic |
Dimensional note: A 150 mm tip length is not a measurement of usable immersion depth, maximum vessel reach, or a guarantee that the tip will fit every 10 mL pipette. Confirm the full instrument-and-tip configuration.
Pipette compatibility: SOCOREX ACURA and CALIBRA macro models
WHEATON's pipette-tip selection chart identifies 851358 as tip reference W for certain 10 mL macropipette models. The chart includes SOCOREX CALIBRA digital, ACURA manual, and ACURA fixed-volume/electro configurations.
The following references come from WHEATON's historical selection information. Because pipette model revisions and tip designs can change, confirm current compatibility against the actual instrument model and manufacturer instructions before standardization.
| WHEATON pipette SKU |
Instrument / model |
Tip reference |
| 851345 |
CALIBRA digital 832, 1–10 mL |
W (851358) |
| W810318 |
ACURA manual 835, 1–10 mL |
W (851358) |
| W810062 |
ACURA 835F, fixed 10 mL |
W (851358) |
The current SOCOREX ACURA manual 835 product family also includes a 1–10 mL instrument configuration. However, this does not establish universal compatibility between historical and current nozzle revisions, different brands, or every accessory variation.
- Confirm the instrument: Identify the full model and volume range.
- Check the nozzle: Verify correct tip engagement and absence of damage.
- Install correctly: Follow the pipette manufacturer's seating and ejection instructions.
- Check the seal: Confirm that aspiration and dispensing occur without abnormal liquid loss or air leakage.
- Verify performance: Perform volumetric checks when required by the laboratory method.
Compatibility rule: A physically fitting tip is not automatically a validated substitute. The nozzle seal, aspiration technique, calibration, tip retention, and correct ejection must be verified for the actual instrument and application.
Air-displacement pipetting and the role of the disposable tip
In an air-displacement pipette, piston movement changes the air volume inside the pipette and tip assembly. This creates the pressure difference used to aspirate or dispense liquid.
The disposable tip serves as the liquid-contact component attached to the pipette nozzle. When correctly installed, the tip forms part of the air-displacement system, while the pipette itself determines the nominal selected volume.
Dispensing performance can change if the tip is poorly seated, the pipette is damaged, the sample is unusually viscous or volatile, or the operator uses an inconsistent technique.
- Pipette calibration: Determines the instrument's volumetric performance under specified test conditions.
- Tip engagement: Must create an appropriate seal to support aspiration and delivery.
- Air displacement: Makes liquid delivery sensitive to technique and fluid characteristics.
- Tip wetting: Can affect liquid retention and repeatability depending on the sample and method.
- Liquid behavior: Viscosity, volatility, foaming, and surface tension can alter the results.
- Operator technique: Immersion depth, plunger speed, orientation, and delivery procedure influence repeatability.
Sterility, filtration, DNase/RNase, and pyrogen-free designations
DWK's current pipette-tip family description mentions high-density filters, DNase/RNase-free options, and sterile or pyrogen-free tips. These are family-level product features, not a confirmation that every WHEATON pipette tip has every feature.
WHEATON's SKU-level tip-selection chart distinguishes the product characteristics of individual catalog numbers. For 851358, the chart does not indicate the presence of a filter, supplied sterility, a DNase/RNase-free designation, or a pyrogen-free designation.
| Characteristic |
851358 designation |
Meaning for selection |
| Aerosol barrier filter |
Not included |
Do not rely on this tip for filter-tip aerosol protection |
| Sterile |
Not designated |
Do not treat the bulk pack as a sterile presentation |
| DNase/RNase-free |
Not designated |
No verified nuclease-free certification for this SKU |
| Pyrogen-free |
Not designated |
No verified pyrogen-free qualification for this SKU |
Sterility, nuclease control, pyrogen control, and filtration are distinct characteristics. A sterile product is not automatically validated as nuclease-free or pyrogen-free. Likewise, an unfiltered tip may be appropriate for some routine laboratory tasks but not for methods requiring aerosol-barrier protection.
Critical selection warning: Do not introduce 851358 into a sterile, molecular-biology, endotoxin-sensitive, or other specially controlled procedure solely on the basis of DWK's general family marketing description. Obtain product-specific qualification evidence or select a tip expressly manufactured and documented for the required purpose.
Filtered versus non-filtered pipette tips: understanding aerosol and carryover risk
Filtered pipette tips incorporate a barrier material intended to reduce the movement of aerosols or liquid contamination toward the pipette nozzle. A regular non-filtered tip lacks that integrated filter barrier.
WHEATON 851358 is a non-filtered macrotip. This does not make it unsuitable for all laboratory use, but it changes the controls required when handling contamination-sensitive, aerosol-generating, or potentially hazardous samples.
- Routine liquid transfer: A compatible non-filtered tip may be suitable when permitted by the method and contamination-control requirements.
- Aerosol-sensitive workflows: Select an appropriately qualified filter-tip system or implement validated protective controls.
- Pipette nozzle protection: Some macro pipette models use separately designated nozzle-protection filters within the instrument.
- Cross-contamination control: Replace disposable tips according to the SOP and avoid aspiration into the pipette body.
- Hazardous materials: Follow the laboratory's risk assessment and approved liquid-handling equipment requirements.
A nozzle-protection filter installed in a compatible pipette is not the same as a filter integrated into the disposable tip. Neither should be substituted for an approved safety procedure without evaluating the intended use.
Polypropylene chemical compatibility and liquid-contact considerations
Polypropylene is widely used for laboratory consumables because it offers useful general-purpose chemical resistance. However, resistance depends on the actual substance, concentration, exposure duration, and temperature.
DWK provides a chemical compatibility calculator and technical information on plastic materials. These resources can help identify whether polypropylene is an appropriate candidate for a particular fluid-transfer application.
| Fluid or condition |
Selection consideration |
| Aqueous laboratory reagents |
Evaluate the actual formulation and sample-integrity requirements |
| Alcohol-containing liquids |
Confirm compatibility for the specific alcohol, concentration, and temperature |
| Organic solvents |
Check for polymer interaction, swelling, adsorption, or degradation |
| Acidic or alkaline solutions |
Assess chemical identity, concentration, and exposure conditions |
| Protein or biological samples |
Evaluate adsorption and required biological purity certifications |
| Sensitive analytical samples |
Consider extractables, leachables, background contamination, and recovery requirements |
The table describes questions to evaluate, not product-specific compatibility ratings. For sensitive or aggressive fluids, consult the manufacturer's chemical compatibility guidance and qualify the actual material under the laboratory's process conditions.
Material qualification: No chemical-specific exposure-time rating, extractables limit, adsorption coefficient, or guaranteed sample-recovery value is assigned to WHEATON 851358 in the reviewed manufacturer specifications.
Review DWK's Chemical Compatibility Calculator
Best-practice pipetting: improve consistency and reduce sample carryover
Correct tip selection is only one component of reliable liquid handling. The instrument's operating instructions and the laboratory's SOP must also define attachment, aspiration, dispensing, and tip replacement procedures.
- Confirm the pipette and tip: Match the instrument model, nozzle, tip capacity, and method requirements.
- Inspect the consumable: Check for cracking, deformation, contamination, or damaged tip openings.
- Seat the tip correctly: Install according to the instrument manufacturer's instructions to obtain a consistent nozzle seal.
- Check the volume setting: Use the pipette within its calibrated operating range.
- Pre-wet when required: Follow the appropriate liquid-handling method for improved consistency when pre-wetting is recommended.
- Maintain correct immersion: Avoid excessive immersion and use the orientation required by the pipette manual.
- Aspirate smoothly: Prevent abrupt plunger release, foaming, and unnecessary air-bubble formation.
- Dispense using the approved technique: Follow the applicable first-stop, blow-out, and receiving-vessel procedure.
- Inspect delivery: Investigate unexpected droplets, liquid retention, or an inconsistent delivered volume.
- Change the tip: Replace tips between samples and whenever required by the SOP.
- Dispose properly: Discard used tips according to the applicable chemical, biological, or laboratory waste procedure.
Method standardization tip: When volumetric results vary between operators, evaluate the tip fit, pipette calibration, immersion depth, liquid-equilibration conditions, plunger speed, and delivery technique before assuming the tip alone is responsible.
Autoclavability, sterile preparation, and processing requirements
Polypropylene products may be manufactured for different preparation and processing methods. The material's general heat resistance does not independently establish that every polypropylene tip can be sterilized using the same autoclave conditions.
WHEATON offers a separately identified autoclaving box for 10 mL pipette tips, manufacturer part number W835150. The existence of this accessory does not itself specify a validated autoclave cycle for the 851358 bulk pack or establish the sterility of the tips as supplied.
The reviewed 851358 SKU-level specifications do not provide a sterilization cycle, sterility assurance level, or verified sterile packaging designation. When sterile use is required, obtain current manufacturer processing information and apply the facility's approved qualification procedure.
- Confirm process suitability: Obtain applicable product-specific information before processing the tips.
- Use a suitable holder: Select an approved rack or processing container that supports the tips without deformation.
- Validate the process: Apply the required loading, sterilization, cooling, and release procedure.
- Inspect afterward: Check for distortion, cracking, tip-fit changes, or other damage.
- Maintain sterile handling: When sterility is required, define the packaging, transfer, and post-processing handling method.
- Record qualification: Maintain documentation appropriate to the intended laboratory or regulated application.
Processing boundary: Do not label WHEATON 851358 as supplied sterile, assign an arbitrary autoclave cycle, or assume validated aseptic-use suitability based solely on general polypropylene properties or the availability of an autoclaving accessory.
Cleanroom and controlled-environment suitability
WHEATON 851358 may be evaluated for liquid-handling applications performed in controlled laboratories or cleanroom environments when the material, packaging, cleanliness, and sterile status meet the facility's requirements.
However, the manufacturer does not assign this SKU an ISO 14644 product classification, verified particle-release level, sterile packaging designation, or cleanroom processing specification in the reviewed product record.
- Material transfer: Follow approved packaging removal and cleanroom introduction procedures.
- Bulk packaging: Evaluate whether the supplied bulk presentation is appropriate for the controlled work area.
- Sterile operations: Do not use an unqualified non-sterile tip in a procedure requiring sterile consumables.
- Particle-sensitive processes: Verify material cleanliness and particulate requirements through product-specific evidence.
- Nuclease-sensitive processes: Select a tip with appropriate manufacturer-supported contamination-control certification.
- Handling discipline: Minimize contamination from gloves, benches, tip containers, and surrounding equipment.
ISO qualification note: ISO 14644 classifies the cleanroom environment, not automatically the pipette tip. A facility's approved SOP and product-specific documentation determine whether this consumable is appropriate for the intended controlled process.
Comparing related WHEATON macro pipette tips
WHEATON's macro pipette-tip range includes different capacities and packaging configurations. Select the tip according to the actual pipette model, required capacity, and handling method.
| WHEATON SKU |
Capacity |
Length |
Packaging |
Qty/Case |
| 851355 |
2 mL |
Approx. 115 mm |
Bulk pack |
250 |
| 851358 |
10 mL |
150 mm |
Bulk pack |
100 |
| W851362 |
5 mL |
Approx. 123 mm |
2 packs of 250 |
500 |
| W851363 |
5 mL |
Approx. 123 mm |
2 racks of 50 |
100 |
The 5 mL W851362 and W851363 variants are identified as graduated in WHEATON's selection documentation, unlike the regular 10 mL 851358 tip. These products are not direct replacements for 851358 simply because they belong to the same family.
Procurement checkpoint: Confirm the exact manufacturer number rather than purchasing based on appearance, packaging count, or a shared WHEATON family name. Tip capacity, length, graduation style, and pipette-nozzle compatibility can differ.
Bulk packaging, storage, and handling requirements
DWK identifies WHEATON 851358 as a bulk pack of 100 tips. Bulk packaging offers a different handling presentation from individually wrapped or pre-racked tips.
The reviewed SKU specifications do not establish a numerical shelf life, storage-temperature range, packaging sterility validation, or cleanroom-grade packaging designation.
- Protect unused tips: Keep tips in their designated storage arrangement until required for use.
- Prevent contamination: Avoid contacting the tip opening or internal fluid-contact surfaces during handling.
- Maintain identification: Preserve the manufacturer part number and required lot information.
- Inspect packaging: Investigate damaged or disturbed bulk packages before release.
- Use appropriate dispensers or holders: Follow facility procedures when transferring bulk tips to a clean rack or workstation.
- Separate processing status: Where applicable, maintain identification of unused, processed, or otherwise qualified material.
Receiving and inspection checklist
Laboratories with purchasing controls should confirm product identity, packaging, and required documentation before releasing the received tips for use.
- Verify the SKU: Confirm WHEATON 851358 against the purchase order.
- Confirm capacity: Check that the received tips are the 10 mL configuration.
- Confirm length: Match the 150 mm manufacturer specification.
- Confirm material and color: Verify natural-color polypropylene.
- Confirm packaging: Verify a bulk pack containing 100 tips.
- Check the filter specification: Confirm that the order requires an unfiltered tip.
- Confirm purity requirements: Do not release for a sterile or specially certified process unless the necessary product-specific documentation has been obtained.
- Inspect physical condition: Check for cracked, deformed, damaged, or visibly contaminated tips.
- Maintain records: Capture required manufacturer identification, lot information, and receiving documentation.
- Release according to SOP: Complete any applicable incoming inspection or qualification procedures.
Important use limitations and unsupported assumptions
- Not a filtered tip: No integrated aerosol barrier filter is designated for this SKU.
- Not documented as supplied sterile: The SKU-level selection chart does not identify 851358 as a sterile product.
- No verified nuclease-free certification: DNase/RNase-free status is not designated for this exact part number.
- No verified pyrogen-free certification: A product-specific pyrogen-free claim is not established.
- No universal instrument fit: Confirm the pipette model and nozzle compatibility.
- No independent volumetric accuracy rating: Accuracy depends on the complete pipette-and-tip system.
- No universal chemical resistance: Polypropylene compatibility must be evaluated against the actual liquid.
- No defined autoclave cycle: Do not assign a product-specific sterilization process without supporting documentation.
- No ISO cleanroom product class: The reviewed SKU documentation does not establish a particle or ISO cleanliness rating.
- No validated sample-recovery specification: Do not assume universal low-retention, low-binding, or extractables performance.
Technical FAQs
What is the exact capacity of WHEATON 851358?
DWK identifies a nominal maximum tip capacity of 10 mL (10,000 µL).
How long are the tips?
The manufacturer specifies an overall tip length of 150 mm, approximately 5.91 inches.
What material are the tips made from?
They belong to WHEATON's high-grade virgin polypropylene pipette-tip family. The manufacturer describes the family material as metal-free polypropylene.
How many tips are supplied in a case?
Part number 851358 is supplied in a bulk pack of 100 tips, with 100 tips per case.
Are the tips supplied in racks?
No. The manufacturer identifies 851358 as bulk packed. A rack is not included in the stated configuration.
Are these filtered pipette tips?
No. WHEATON's individual tip-selection chart does not identify 851358 as filtered. Filtered variants elsewhere in the product family should not be confused with this SKU.
Are WHEATON 851358 tips sterile?
The manufacturer SKU-level selection chart does not designate 851358 as sterile. It should therefore not be represented as a supplied-sterile consumable without additional manufacturer confirmation.
Are the tips DNase/RNase-free or pyrogen-free?
Those designations are not indicated for this specific SKU in WHEATON's selection chart. Obtain suitable product-specific documentation if required.
Are the tips compatible with SOCOREX macropipettes?
WHEATON's historical selection chart identifies the 10 mL tip with selected ACURA manual, ACURA fixed-volume, and CALIBRA digital macropipette configurations. Confirm compatibility with the actual instrument and nozzle revision.
Does the tip determine the precision of a pipette?
Not by itself. Volumetric performance depends on the pipette's calibration, tip fit, liquid properties, and operator technique.
Can WHEATON 851358 be used with any 10 mL pipette?
No universal compatibility claim has been established. Verify nozzle fit and dispensing performance with the specific instrument.
Can these polypropylene tips be autoclaved?
General polypropylene material properties and the availability of an autoclaving-box accessory do not establish a specific validated cycle for 851358. Request current manufacturer guidance if processing is required.
Can the tips be used for molecular biology applications?
Suitability depends on the method. No product-specific DNase/RNase-free, sterile, or pyrogen-free qualification is established in the reviewed documents, so applications requiring those attributes should use appropriately documented consumables.
Do these tips contain a calibrated 10 mL graduation?
The manufacturer identifies a regular 10 mL macrotip rather than a graduated variant. Do not use the tip itself as a calibrated measuring vessel.
What is the difference between 851358 and W851363?
851358 is a 10 mL, 150 mm bulk macrotip supplied 100 per case. W851363 is a 5 mL tip supplied in two racks of 50 tips, with a shorter published length.
Are the tips reusable?
They are sold as disposable pipette-tip consumables. Reuse should not be assumed acceptable without an approved process and supporting qualification.
Manufacturer documentation and technical references
The manufacturer product record confirms the catalog number, capacity, length, color, and bulk quantity. WHEATON's detailed pipette-tip selection chart provides additional configuration and historical instrument-fit information. No verified direct manufacturer-hosted, SKU-specific technical PDF was identified for customer linking.
Why purchase WHEATON pipette tips from SOSCleanroom?
- Exact-SKU sourcing: SOSCleanroom can assist with identifying the correct WHEATON tip capacity, material, style, and packaging configuration.
- Pipette compatibility support: Our team can help locate available manufacturer information for specific liquid-handling instruments.
- Documentation assistance: Request help identifying product specifications, technical references, and applicable quality documentation.
- Configuration control: Maintain distinction between standard, filtered, sterile, bulk, and racked pipette-tip configurations.
- Centralized laboratory purchasing: Source laboratory consumables and critical-environment products through Specialty Optical Systems, Inc.
- Responsive customer service: Contact SOSCleanroom directly for pricing, availability, and purchasing assistance.
If you have any questions please email us at Sales@SOSsupply.com or give us a call at (214) 340-8574.
For additional product guidance, use the SOSCleanroom AI ChatBot or contact our team for manufacturer documentation assistance.
Technical insight: Reliable macro pipetting requires the correct tip capacity and nozzle fit, validated volumetric performance, consistent handling technique, and a consumable whose filtration and purity designations match the laboratory method.
Last updated: October 26, 2026
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