The Technical Vault
By SOSCleanroom
15-415 Thread
Black Phenolic
PTFE-Faced 14B Rubber
Solid Top
Autoclavable
200/Case
WHEATON 240463: Thread Compatibility, Liner Construction, and Seal Performance
The WHEATON® 240463
is a 15-415 black phenolic
solid-top screw cap with a
PTFE-faced 14B rubber liner.
Its closure design combines a phenolic
cap body, chemically resistant PTFE
contact facing, and resilient
styrene-butadiene rubber backing.
Successful closure selection requires
more than matching a nominal cap size.
The container's thread finish,
liner material, sealing rim,
sample chemistry, and application
conditions must be considered together.
Technical takeaway:
SKU 240463 uses a
15-415 finish.
It should not be treated as
interchangeable with the
13-425 WHEATON 240408 or
the 15-425 WHEATON 240409,
even though all three use
PTFE/14B rubber liner constructions.
Core Product Specifications
| Specification |
WHEATON 240463 |
| Manufacturer |
DWK Life Sciences |
| Brand |
WHEATON® |
| Catalog number |
240463 |
| Product category |
Caps and closures |
| Closure type |
Screw-thread cap |
| Cap material |
Phenolic |
| Cap color |
Black |
| Thread finish |
15-415 |
| Cap style |
Solid top |
| Liner type |
PTFE-faced 14B rubber |
| Liner-facing material |
PTFE |
| General facing thickness |
0.005 inch in the DWK PTFE/14B technical guide |
| Rubber backing |
White sulfur-cured styrene-butadiene rubber |
| Autoclavable |
Yes, per manufacturer specification |
| Case quantity |
200 caps |
| Purchase unit |
Case |
| Container included |
No |
| Country of origin |
United States, per manufacturer item-setup data |
No product-specific application
torque, quantified leak-rate
specification, liner thickness
tolerance, cap-height tolerance,
or certified external diameter
is established in the reviewed
catalog information.
Understanding the 15-415 Thread Finish
The 15-415 designation
identifies the cap's nominal
screw-thread finish. The first
number refers to the nominal
closure diameter designation;
the second identifies the
thread-style specification.
DWK explains that the thread
finish on a closure and container
must correspond. For example,
a 15-415 cap
should be used with a
compatible 15-415 neck finish.
A 15-425 closure may share
the same nominal diameter
designation but has a
different thread style.
It must not be assumed
to provide proper engagement,
liner compression, or
sealing on a 15-415 container.
Compatibility rule:
Match the entire
15-415 designation,
not just the number 15.
Then verify the actual
cap-and-container fit
and sealing performance.
PTFE/14B Rubber: Two-Layer Liner Construction
DWK's Closure Liner Guide describes
its PTFE/14B construction as
virgin PTFE bonded to
white sulfur-cured styrene-butadiene
rubber. The guide identifies
a nominal 0.005-inch PTFE
facing for this general
liner type.
| Component |
Material |
Role |
| Sample-contact facing |
PTFE |
Provides a chemically resistant surface at the intended sealing interface |
| Compressible backing |
14B SBR rubber |
Adds compliance and resilience to the liner assembly |
| Cap body |
Phenolic |
Provides the screw-threaded closure structure |
The PTFE-facing material
and the underlying rubber
perform different functions.
The PTFE helps provide the
chemically resistant contact
surface, while the rubber
backing permits the liner
to compress against the
container rim.
Material distinction:
WHEATON 240463 is not
an all-PTFE cap.
The underlying rubber
and phenolic materials
still need to be considered
when evaluating the
completed closure system.
Chemical Compatibility and Sample Integrity
PTFE is widely used for its
chemical resistance, and
DWK describes the facing
in this liner design as
an inert sample-contact surface.
However, product compatibility
depends on more than the
PTFE-facing material. The
laboratory should evaluate
the sample's potential contact
with the liner edge, rubber
backing, cap body, and
other parts of the assembly
under actual use conditions.
| Factor |
Qualification Consideration |
| Chemical identity |
Review the actual solvent, reagent, or mixture |
| Concentration |
Evaluate at the intended formulation strength |
| Temperature |
Consider storage, handling, and processing conditions |
| Contact time |
Distinguish short-term exposure from prolonged storage |
| Analytical sensitivity |
Check extractables, leachables, or sample interactions where required |
| Seal performance |
Qualify leakage or evaporation under actual conditions |
The manufacturer's general
liner description does not
establish a universal solvent
rating, extractables specification,
or approved storage duration
for every sample.
Comparing WHEATON 240408, 240463, and 240409
The three WHEATON closures below
share black phenolic construction
and PTFE-faced rubber liners,
but differ in thread finish.
| SKU |
Finish |
Liner |
Case Quantity |
| 240408 |
13-425 |
PTFE/14B rubber |
200 |
| 240463 |
15-415 |
PTFE/14B rubber |
200 |
| 240409 |
15-425 |
PTFE/14B rubber |
200 |
All three have a solid-top
phenolic cap and are
manufacturer-listed as
autoclavable. Nevertheless,
each uses a different
catalog identity or
thread finish.
Ordering caution:
Do not substitute a 15-425
cap for a 15-415 cap.
Contact SOSCleanroom to
identify the correct closure
for the intended container.
PTFE-Faced Rubber vs. Other Closure Liner Materials
The sample-contact facing
and backing material both
influence closure selection.
DWK offers several liner
constructions with different
mechanical and chemical
characteristics.
| Liner |
Construction |
Selection Note |
| Plain 14B rubber |
Styrene-butadiene rubber |
Resilient liner with limitations for oils, strong acids, and hydrocarbons |
| PTFE/14B rubber |
PTFE bonded to SBR backing |
This product's liner type; chemically resistant PTFE facing with resilient backing |
| PTFE/silicone |
PTFE facing on silicone rubber |
Different backing selected for certain specialized storage applications |
| PTFE/PE foam |
PTFE facing on polyethylene foam |
Different compressibility and sealing characteristics |
These are general material
comparisons, not claims that
each liner type is available
in a particular 15-415 cap.
Confirm the catalog-specific
configuration before ordering.
Liner Compression, Leak Resistance, and Torque
The cap functions by
compressing its liner
against the mouth of a
compatible container.
The effectiveness of this
interface depends on the
liner condition, rim geometry,
thread engagement, and
closure application procedure.
DWK recommends testing
closure liners for
leak-resistant applications.
It does not establish
a universal torque range
or leakage limit for
every container used
with WHEATON 240463.
- Thread fit: Confirm the correct 15-415 finish.
- Rim condition: Check for chips, defects, contamination, or residue.
- Liner condition: Check the PTFE surface, backing, and placement.
- Application: Use an approved tightening and handling method.
- Qualification: Test for leakage, evaporation, or sample loss as required by the application.
Autoclavability and Sterility Considerations
The manufacturer identifies
WHEATON 240463 as
autoclavable.
DWK's technical guide also
identifies its PTFE/14B
rubber liner construction
as autoclavable.
That designation does not
establish an approved cycle
for every filled, tightly
capped, or chemically
sensitive container assembly.
The complete configuration
must be qualified for the
intended processing conditions.
Critical distinction:
Autoclavable does not mean
supplied sterile.
The reviewed manufacturer
records do not establish
a supplied-sterile status,
validated product-specific
autoclave cycle, or
sterility assurance level.
Solid-Top Cap vs. Open-Top Septum Closure
WHEATON 240463 is a
solid-top cap.
It is not an open-top
closure designed to
expose a pierceable septum.
Although the liner contains
rubber, the cap's closed
top does not provide a
designated syringe-access
opening. Repeated needle
puncture, self-sealing
performance, and autosampler
compatibility are not
established for this product.
For applications requiring
sample withdrawal through
a septum, select a
separately qualified
open-top closure and
compatible septum system.
Material-Level Regulatory and Technical Documentation
DWK's general PTFE/14B
liner description references
FDA 21 CFR 177.1550 for
the PTFE material.
The same guide describes
the 14B backing as
white sulfur-cured
styrene-butadiene rubber.
These statements describe
manufacturer material
information. They do not
independently certify
the finished WHEATON 240463
closure for a particular
pharmaceutical, food-contact,
medical-device, or
sterile application.
Contact SOSCleanroom
for additional manufacturer
documentation when the
intended application has
regulated material or
quality-system requirements.
Cleanroom and Controlled-Environment Considerations
The presence of a PTFE-faced
liner does not automatically
qualify a closure for
sterile manufacturing
or a defined ISO
cleanroom classification.
The reviewed 240463 records
do not establish supplied
sterility, a particulate
release specification,
an endotoxin limit,
or a product-specific
extractables and leachables
qualification. Facilities
should apply their own
material acceptance and
contamination-control criteria.
Receiving and Inspection Checklist
- Verify SKU: Confirm WHEATON 240463.
- Check thread finish: Confirm 15-415, not 15-425 or 13-425.
- Confirm quantity: Verify 200 caps per case.
- Inspect phenolic cap: Check for cracks, visible defects, and damaged threads.
- Inspect liner: Confirm PTFE/14B rubber material and correct liner seating.
- Inspect facing: Look for contamination, separation, or damage.
- Verify container: Confirm a compatible 15-415 neck and appropriate sealing rim.
- Review processing: Follow the approved cap and container preparation procedure.
- Maintain traceability: Apply the laboratory's material identification and acceptance requirements.
Technical FAQs
What is WHEATON 240463?
A black phenolic
15-415 solid-top
screw cap with a
PTFE-faced 14B
rubber liner.
What thread finish does it use?
15-415. The container
must have a compatible
matching neck finish.
Can I replace a 15-425 cap with 240463?
Not without separately
establishing compatibility.
The 15-415 and 15-425
designations specify
different thread styles.
Is this the same as WHEATON 240408?
No. Both use PTFE-faced
rubber liners, but
240408 has a 13-425
finish, while 240463
has a 15-415 finish.
Is the liner made entirely of PTFE?
No. It is PTFE
facing bonded to
14B styrene-butadiene
rubber backing.
What is the thickness of the PTFE facing?
DWK's general PTFE/14B
rubber liner guide
describes a 0.005-inch
PTFE-facing layer.
No SKU-specific
tolerance is established.
Why use a PTFE-faced liner?
It provides a chemically
resistant surface
at the intended
sample-contact interface,
while the rubber
backing provides
compressibility.
Is it compatible with organic solvents?
The PTFE facing offers
chemical-resistance benefits,
but the actual solvent
and complete assembly
must be evaluated.
Is this cap autoclavable?
Yes. DWK identifies
SKU 240463 as
autoclavable.
The complete procedure
still requires
application qualification.
Is it supplied sterile?
The reviewed product
records do not
establish a supplied
sterile designation.
Is it a pierceable septum cap?
No. This is a
solid-top screw cap,
not an open-top
access closure.
Does the cap guarantee a leakproof seal?
No universal leakproof
guarantee is established.
DWK recommends testing
liners for leak-resistant
applications.
How many caps are in a case?
200 caps per case.
Containers are
sold separately.
Manufacturer Technical Documentation
The DWK Closure Liner Guide
provides general technical
information about liner materials,
PTFE-facing construction,
thread-finish identification,
and selecting liners for
laboratory containers.
Documentation boundary:
General manufacturer material
information does not constitute
a finished-product sterility
certificate, leakproof guarantee,
or universal chemical
compatibility certification.
Contact SOSCleanroom to
request additional available
documentation if required.
Technical Assistance and Ordering Support
SOSCleanroom can help
verify 15-415 container
compatibility, select
PTFE-faced closures,
compare 13-425 and
15-425 alternatives,
and obtain manufacturer
technical documentation.
Need help matching
a cap to a laboratory vial?
Contact SOSCleanroom for
pricing, availability,
liner selection,
and ordering assistance.
Email:
Sales@SOSsupply.com
Phone:
(214) 340-8574
For product specifications,
purchasing, availability,
and technical support,
contact SOSCleanroom
at Sales@SOSsupply.com
or (214) 340-8574.
Technical insight:
A successful closure must
match the container's
thread finish and the
application's chemical
and sealing requirements.
WHEATON 240463 requires
a compatible 15-415 finish.
Last updated:
October 23, 2026
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(dba SOSCleanroom). All rights reserved.